KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA4
All Species:
26.67
Human Site:
T568
Identified Species:
39.11
UniProt:
O75676
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75676
NP_001006945.1
772
85606
T568
S
P
G
V
P
M
Q
T
P
C
F
T
L
Q
Y
Chimpanzee
Pan troglodytes
XP_508900
901
98668
T697
S
P
G
V
P
M
Q
T
P
C
F
T
L
Q
Y
Rhesus Macaque
Macaca mulatta
XP_001114877
772
85557
T568
S
P
G
V
P
M
Q
T
P
C
F
T
L
Q
Y
Dog
Lupus familis
XP_854926
772
85603
T569
S
P
A
G
P
M
Q
T
P
C
F
T
L
Q
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
T568
S
P
A
E
P
M
Q
T
P
C
F
T
L
Q
Y
Rat
Rattus norvegicus
Q63531
735
82865
G530
V
E
Y
L
H
S
Q
G
V
V
H
R
D
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
T498
P
D
N
Q
P
L
K
T
P
C
F
T
L
H
Y
Chicken
Gallus gallus
Q5F3L1
789
89022
T571
P
D
N
Q
P
L
K
T
P
C
F
T
L
H
Y
Frog
Xenopus laevis
P10665
733
82620
G528
V
E
N
L
H
S
Q
G
V
V
H
R
D
L
K
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
K539
G
V
V
H
R
D
L
K
P
S
N
I
L
Y
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
L780
K
D
K
P
R
Y
T
L
D
Y
A
P
P
E
M
Honey Bee
Apis mellifera
XP_395099
910
102507
T600
R
G
C
E
P
L
H
T
P
C
F
T
L
P
Y
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
P547
Q
V
L
R
K
M
T
P
C
F
T
L
Q
Y
A
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
S541
P
L
K
T
P
C
F
S
L
H
F
A
A
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
L270
D
L
K
P
E
N
I
L
M
D
V
D
G
H
V
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
D476
K
P
E
N
I
L
L
D
Y
Q
G
H
I
A
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
98.6
96.7
N.A.
95.8
41.3
N.A.
56
64
41
41.9
N.A.
27
45.1
48.1
48.2
Protein Similarity:
100
85.6
98.9
98
N.A.
96.7
60.6
N.A.
71.6
78.4
59
60.3
N.A.
38.9
60.1
64.3
61.8
P-Site Identity:
100
100
100
86.6
N.A.
86.6
6.6
N.A.
53.3
53.3
6.6
13.3
N.A.
0
53.3
6.6
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
13.3
N.A.
66.6
66.6
13.3
13.3
N.A.
6.6
60
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
0
0
0
0
0
0
0
7
7
7
7
7
% A
% Cys:
0
0
7
0
0
7
0
0
7
50
0
0
0
0
0
% C
% Asp:
7
19
0
0
0
7
0
7
7
7
0
7
13
0
0
% D
% Glu:
0
13
7
13
7
0
0
0
0
0
0
0
0
7
7
% E
% Phe:
0
0
0
0
0
0
7
0
0
7
57
0
0
0
0
% F
% Gly:
7
7
19
7
0
0
0
13
0
0
7
0
7
0
0
% G
% His:
0
0
0
7
13
0
7
0
0
7
13
7
0
19
0
% H
% Ile:
0
0
0
0
7
0
7
0
0
0
0
7
7
0
0
% I
% Lys:
13
0
19
0
7
0
13
7
0
0
0
0
0
0
13
% K
% Leu:
0
13
7
13
0
25
13
13
7
0
0
7
57
13
7
% L
% Met:
0
0
0
0
0
38
0
0
7
0
0
0
0
0
13
% M
% Asn:
0
0
19
7
0
7
0
0
0
0
7
0
0
0
0
% N
% Pro:
19
38
0
13
57
0
0
7
57
0
0
7
7
13
0
% P
% Gln:
7
0
0
13
0
0
44
0
0
7
0
0
7
32
0
% Q
% Arg:
7
0
0
7
13
0
0
0
0
0
0
13
0
0
0
% R
% Ser:
32
0
0
0
0
13
0
7
0
7
0
0
0
0
0
% S
% Thr:
0
0
0
7
0
0
13
50
0
0
7
50
0
0
0
% T
% Val:
13
13
7
19
0
0
0
0
13
13
7
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
7
0
0
7
7
0
0
0
13
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _